1H-Indazole, 4-chloro-3-phenyl- - Names and Identifiers
1H-Indazole, 4-chloro-3-phenyl- - Physico-chemical Properties
Molecular Formula | C13H9ClN2
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Molar Mass | 228.68 |
Boling Point |
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Storage Condition | 2-8°C |
1H-Indazole, 4-chloro-3-phenyl- - Introduction
4-Chloro-3-phenyl-1H-indazole is an organic compound with the chemical formula C11H7ClN. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: 4-Chloro-3-phenyl-1H-indazole is a colorless to pale yellow crystalline powder.
-Melting point: about 171-173°C.
-Solubility: Soluble in organic solvents (such as ethanol, dimethyl sulfoxide, etc.), insoluble in water.
Use:
-4-Chloro-3-phenyl-1H-indazole is an important intermediate compound, which has a wide range of applications in pharmaceutical, pesticide and other fields.
-It can be used to synthesize a variety of active chemical substances, such as drugs, pesticides, dyes, etc.
Preparation Method:
-4-Chloro-3-phenyl-1H-indazole has many preparation methods, the following is a common synthetic route:
1. First, benzoic acid reacts with nitrous acid to obtain nitrosyl benzoate.
2. Nitrosobenzoate is then reacted with chloroacetic acid to form 4-chloro-3-phenylindazole-5-carboxylic acid.
3. Finally, by reduction and acid catalysis, 4-chloro-3-phenylindazole-5-carboxylic acid is converted to 4-chloro-3-phenyl-1H-indazole.
Safety Information:
-4-Chloro-3-phenyl-1H-indazole is a chemical and should be used with caution.
-Avoid inhalation, ingestion or contact with skin, and pay attention to protective measures, such as wearing protective glasses, gloves, etc.
-Pay attention to good ventilation conditions during use.
-storage should be stored in a dry, dark, well-ventilated place, away from fire and flammable materials.
Last Update:2024-04-09 21:01:54